Our Alliance is focussing on SDLs for adapting imaging systems to spatial transcriptome and proteome data, for mapping regulatory networks, for the inverse design of microbiomes, for developing adaptive biomaterials and polymers for implants and for use in bioelectronics, as well as for automated cell culture, implant performance and the analysis of biological processes. Another focus is the scale-up of biomedical innovations in a digital, autonomous pilot process, e.g. for the production of novel personalized active ingredients or highly intelligent material systems for new sensors or wearables. The SDL network at the two sites are open core facilities that support the research and development work of the Helmholtz Centers KIT and Hereon and its partners from science, industry and government.

With our chemistry SDL we will accelerate experimental screening cycles by utilizing automated chemical synthesis workflows
link
Central foundry for training data sets for the autonomous discovery of biomaterials for printable bioinks
link
Autonomous high-throughput development of 3D tissues and organoids, assembloids and synthetic tissues with completely new properties
link
Autonomous pipeline for omics sequencing and spatial transcriptomics as well as multiplexing also for training simple microscopy

Synthesis of hierarchically structured or clustered particulate biomaterials with controlled size, shape and morphology
link
SURMOF-based substrates for cell adhesion and storage of bioactive molecules in SURMOF pores

Targeted development and optimization of novel analytical methods for bormal and pathological tissues using automated screening procedures
link
Autonomous bioproduction platform for safe and renewable food production and the production of novel biomes from CO2 and green H2

Adapted version of the successful reinforcement learning based beam control and analysis and microfluidic NMR labs
Development and integration of electronic materials, components and systems for in vivo sensors, wearables, new chip technologies

Automated development of miniaturized acceleration testing technologies (Accelerate.RT) by integrating automated sample handling techniques from the Helmholtz synchrotron radiation beamline
linkProduction of the optimized products in a digital process design, including the design of the individual devices and systems through autonomous process chains