The aim of the Bio.MAT SDL is to create a central foundry for training data sets for the autonomous discovery of biomaterials, in particular for printable bioinks in analogy to the Polymer Genome project. To this end, an integrated platform will be established that enables both the automated synthesis of printable bioinks and an automated 3D bioprinting process of these inks together with biological materials such as cells. An integrated rheological characterization of the materials and an analysis, e.g. by automated imaging of cellular parameters such as cytotoxicity, proliferation, differentiation, migration and adhesion of the cells as well as other parameters such as tissue integrity and shelf life, then generate the corresponding data sets, which are later available for an inverse design of the material development.  The data is collected via the Chemotion (LabImotion) ELN and repository and stored in the Bio.MAT Foundry.

The connection to our SDL Tissue & Organoids (Bio.LAB) containing the automated platform for the cultivation and differentiation of induced pluripotent stem cells (iPSCs) to 3D tissues will strengthen the automated high-throughput development process. This unique combination of robotics in high-throughput methods and handling from synthesis to final handling and biotesting of biomaterials and the integration with artificial intelligence enables learning through direct assessment of biological responsiveness to the material.